Description
Description
5-Sulfosalicylic Acid Dihydrate For Electrophoresis ≥99% 500 Gram
Synonym: 2-Hydroxy-5-sulfobenzoic acid
- CAS Number 5965-83-3
- Linear Formula HO3SC6H3-2-(OH)CO2H·2H2O
- Molecular Weight 254.21
- Beilstein/REAXYS Number 650741
- EC Number 202-555-6
- MDL number MFCD00149540
- PubChem Substance ID 24899547
- NACRES NB.22
| grade | for electrophoresis |
| assay | ≥99% |
| impurities | ≤0.02% Insoluble matter |
| ≤0.05% Salicylic Acid | |
| mp | 105-110 °C (lit.) |
| solubility | water: soluble 100 mg/mL, clear, colorless |
| anion traces | chloride (Cl-): ≤0.001% |
| sulfate (SO42-): ≤0.035% | |
| cation traces | Fe: ≤0.001% |
| heavy metals (as Pb): ≤0.002% | |
| SMILES string | [H]O[H].[H]O[H].OC(=O)c1cc(ccc1O)S(O)(=O)=O |
| InChI | 1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2 |
| InChI key | BHDKTFQBRFWJKR-UHFFFAOYSA-N |
General description
5-Sulfosalicylic acid is a strong acid capable of protonating water. It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS). It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.
Application
5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate].
Safety Information
GHS05
Signal word Danger
Hazard statements H314
Precautionary statements P260-P280-P301 + P330 + P331-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RIDADR UN 3261 8 / PGII
WGK Germany 1
Documents
Safety Data Sheet
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