HTG Molecular Microplate ArrayPlate 96 Well qNPA 2 Packs of 10 Plates Each

Description

HTG Molecular ArrayPlate 96-Well Microplate – qNPA Quantitative Nuclease Protection Assay Technology, Pre-Barcoded Automation Framing, Calibrated for the HTG Edge System (MPN: 87251)

The HTG Molecular 87251 is an instrument-grade, specialized 96-well ArrayPlate microplate engineered explicitly for high-throughput gene expression profiling and multiplexed RNA quantification on the automated HTG Edge/EdgeSeq platform. Utilizing HTG’s proprietary Quantitative Nuclease Protection Assay (qNPA) technology, this highly specialized microplate serves as the primary solid-phase substrate where target-specific RNA probe hybridization takes place. Designed to simplify molecular oncology work without requiring laborious RNA extraction or cDNA synthesis, it features an integrated, high-contrast linear barcode permanently attached to the structural skirt. This pre-barcoded architecture interfaces with the laser scanning modules of the HTG Edge automation platform, enabling absolute sample-to-well tracking, error-free processing validation, and complete compliance during large-scale clinical sample screens.

Technical Performance and Design

• qNPA Molecular Substrate Optimization: Developed as a surface-activated execution matrix optimized to securely capture nuclease protection probes. This enables precise target screening directly from raw, unpurified lysates, including challenging formalin-fixed paraffin-embedded (FFPE) tissue biopsies, whole blood, and cell pellets.

• Pre-Barcoded System Automation Tracking: Fabricated with an ultra-durable, solvent-resistant linear barcode. This allows robotic plate handlers and the processing chamber scanners to automatically verify sample data, eliminating manual logging errors.

• Rigid ANSI/SLAS Skirt Dimensions: Molded from a thermally stable, low-profile polymer blend that eliminates warping during warm incubator cycles. The precise physical footprint ensures smooth alignment with robotic gripper decks, automated fluid aspirators, and plate stackers.

• Minimized Cross-Talk Array: Features a specialized optical well layout engineered to isolate luminescent or fluorescent read signals. This design prevents light bleeding between adjacent wells, ensuring high accuracy for low-abundance gene expression profiles.

Product Specifications

• Catalog Number / MPN: 87251

• Manufacturer / Brand: HTG Molecular Diagnostics, Inc.

• Plate Layout Format: Standard 96-Well Microplate Grid (12 x 8 orientation)

• Core Processing Assay: qNPA (Quantitative Nuclease Protection Assay) Sequencing & Screening

• Tracking Integration Profile: Factory-Applied Linear Barcode Matrix on Side Skirt Frame

• System Hardware Compatibility: Calibrated for exclusive automated use inside the HTG Edge and HTG EdgeSeq System fluidic platforms

• Material Composition: Specially treated, medical-grade low-fluorescence polymer matrix

Key Benefits and Applications

• FFPE Tumor Tissue Profiling: The primary assay target used by oncology core facilities to profile multiplexed gene signatures from thin slices of archived tumor blocks without causing extraction-induced sample loss.

• Biomarker Discovery & Immuno-Oncology: Extensively deployed across translational research labs to analyze immune response panels, tumor microenvironments, and target pathways from small biological volume inputs.

• Streamlined Target Extraction Workflows: Direct-to-plate lysis mechanics bypass long chemical isolation protocols, drastically cutting hands-on labor times and ensuring excellent sample-to-sample reproducibility metrics.

• Contamination-Protected Protection: Shipped in protective packaging to minimize ambient static charge, keeping the treated well bottoms free of environmental dust and particulates that could scatter optical signals during detection passes.

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