Pall Syringe Filter 0.2 um Supor Membrane PES 25 mm Diameter Box of 50 Filters

Description

Pall 4187 Acrodisc® PF 25 mm Syringe Filter (0.8/0.2 µm Supor® PES, Sterile)

The Pall 4187 Acrodisc® PF is a high-performance, sterilizing-grade syringe filter engineered for the rapid processing of particulate-laden or viscous biological fluids. This professional-grade filter features a unique “PF” (Pre-Filter) architecture, combining a 0.8 µm pre-filter layer with a 0.2 µm final Supor® (polyethersulfone) membrane. This dual-layer construction significantly increases total throughput and prevents premature clogging, making it the industry standard for filtering cell culture media, serum-rich solutions, and complex buffers. Manufactured with a color-coded (blue/green) modified acrylic housing, each filter is individually blister-packed and gamma-sterilized to ensure absolute purity and compliance with stringent laboratory protocols.

Technical Performance and Design

• Dual-Layer Supor® Technology: The 0.8/0.2 µm graduated pore structure provides built-in pre-filtration, allowing for faster flow rates and up to double the throughput of standard filters when handling “dirty” samples.

• Low Protein Binding: The inherently hydrophilic Supor® (PES) membrane is optimized for minimal non-specific binding, ensuring maximum recovery of high-value proteins, enzymes, and active pharmaceutical ingredients.

• Gamma-Sterilized Purity: Individually sealed in medical-grade blister packs and sterilized via gamma irradiation to eliminate potential EtO (Ethylene Oxide) residuals, making them safe for sensitive cell culture and clinical research.

• Robust Housing Design: The 25 mm modified acrylic housing is designed to withstand operating pressures up to 75 psi (5.2 bar), featuring a female Luer-lock inlet and a male slip Luer outlet for secure connectivity.

Product Specifications

• Catalog Number: 4187

• Diameter: 25 mm

• Membrane Type: Supor® (Hydrophilic Polyethersulfone / PES)

• Pore Size: 0.8/0.2 µm (Integrated Pre-filter + Final Sterilizing Layer)

• Effective Filtration Area: 2.8 cm²

• Hold-up Volume: < 300 µL (with air purge)

• Sterility: Sterile (Gamma Irradiated); Non-pyrogenic.

• Packaging: Individually Sealed Blister Packs (50 per box).

Key Benefits & Applications

• Media & Serum Filtration: The primary choice for sterilizing FBS (Fetal Bovine Serum) and other serum-supplemented media where high particulate loads typically cause filter failure.

• Protein Purification: Ideal for clarifying protein-rich fractions and biological intermediates after chromatography or extraction steps.

• Viscous Solution Processing: Optimized for filtering viscous buffers or viscous biological reagents that require high-pressure manual filtration.

• Sample Preparation: Provides an efficient, single-step method for both clarification and sterilization of small volumes (up to 100 mL) in a single device.

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