Description
MP Biomedicals 6935050 Lysing Matrix F – 15 mL Tubes, Aluminum Oxide & Silicon Carbide
The MP Biomedicals 6935050 (Manufacturer No. 116935050) Lysing Matrix F is a highly specialized sample preparation consumable engineered for the homogenization of tough, hard, or brittle samples where low shear force is required. Each 15 mL tube is pre-filled with an optimized blend of 1.6 mm aluminum oxide and 1.6 mm silicon carbide particles. This unique, angular matrix combination is designed to deliver high-impaction crushing power while minimizing the aggressive mechanical shearing associated with silica or garnet beads. This makes Matrix F the ideal choice for isolating intact organelles, super-molecular structures, and high-yield RNA/proteins from tissues where standard matrices are too destructive. The 15 mL bulk processing format allows researchers to process large-volume tissue sections or pooled cell cultures in a single, secure, and aerosol-free step.
Technical Performance and Design
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Dual-Particle Matrix: Combines the high density of aluminum oxide with the extreme hardness of silicon carbide to effectively crack resilient cell walls and membranes without shredding the internal cellular contents.
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High Impaction, Low Shearing: The irregular, angular shape of the crystals provides powerful blunt-force impaction, perfectly balancing tissue disruption with the preservation of delicate structural complexes and labile proteins.
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15 mL “TeenPrep” Format: The heavy-duty 15 mL tubes easily accommodate larger sample masses (up to 1.5 grams) and higher buffer volumes, drastically increasing extraction throughput compared to standard 2 mL microcentrifuge tubes.
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Impact-Resistant Construction: Engineered with robust polymers and leak-proof caps to withstand the intense, multidirectional G-forces of high-speed bead beating, preventing sample loss and cross-contamination.
Product Specifications
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Catalog Number: 6935050 (Manufacturer No. 116935050)
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Matrix Type: Matrix F (1.6 mm Aluminum Oxide & 1.6 mm Silicon Carbide)
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Tube Size: 15 mL (with secure screw caps)
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Target Samples: Animal and plant tissues, Gram +/- bacteria, mold, fungi, and coral emulsions.
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Quantity: 50 Tubes per pack
Key Benefits & Applications
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Organelle Isolation: The premier matrix choice for researchers isolating intact mitochondria, chloroplasts, and nuclei, where harsh shearing would rupture the delicate organelle membranes.
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High-Fidelity Protein Extraction: Minimizes the mechanical degradation and heat buildup that can denature sensitive enzymes and compromise downstream proteomic analysis.
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Tough Matrix Breakdown: Highly effective at processing difficult biological samples, such as hard plant roots, spores, or coral, without chemically binding the extracted nucleic acids.
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Instrument Compatibility: Designed specifically for the MP Biomedicals FastPrep-24 and FastPrep-96 systems equipped with the 15 mL “TeenPrep” adapters, as well as other compatible high-power laboratory bead mills.
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