GE Xuri Cell Expansion System W5 120V with Warranty

Description

GE Xuri Cell Expansion System W5 – 120V Benchtop Rocking Bioreactor

The GE Xuri Cell Expansion System W5 is a specialized rocking platform designed for small-scale cell culture and early-stage process development in cell therapy manufacturing. By utilizing the proven wave-rocking technology, the W5 provides a gentle, low-shear environment that optimizes gas exchange and nutrient distribution for sensitive suspension cell lines, such as T cells and NK cells. The system is engineered to work with single-use Cellbag bioreactors, creating a functionally closed environment that eliminates the need for cleaning and sterilization validation (CIP/SIP) while significantly reducing the risk of cross-contamination. With its compact footprint and intuitive controls, the W5 is an essential tool for translational research laboratories transitioning from flask-based methods to automated, scalable bioreactor processes.

Technical Performance and Design

• Wave-Rocking Technology: Induces a gentle wave motion within the Cellbag to provide efficient oxygenation and mixing without the high shear stress associated with stirred-tank impellers, preserving cell viability and phenotype.

• Closed-System Processing: Designed for use with gamma-irradiated, single-use Cellbag bioreactors, ensuring an aseptic environment for the expansion of high-value patient-derived cells.

• Adjustable Rocking Parameters: Features precise control over rocking speed (typically 2 to 40 rpm) and rocking angle (2° to 12°), allowing for the optimization of oxygen transfer rates (OTR) based on specific culture requirements.

• Integrated Heating & Temperature Control: Equipped with a built-in heating mat and sensors to maintain a stable incubation temperature, essential for consistent cell growth and metabolic activity.

Product Specifications

• Model: Xuri Cell Expansion System W5 (120V Edition)

• Working Volume: 0.3 L to 5 L (Total capacity up to 10 L Cellbags)

• Rocking Speed Range: 2 – 40 rpm

• Rocking Angle: 2° – 12°

• Electrical Requirements: 110-120V, 50/60 Hz

• Compatibility: Optimized for T-cells, NK-cells, and MSC expansion.

• CO2 Control: Compatible with external CO2 mixers (e.g., CO2MIX20) for pH regulation.

Key Benefits & Applications

• Cell Therapy Research: Ideally suited for the production of T cells for adoptive immunotherapy, consistently reaching high cell densities (> 10^7 cells/mL) through perfusion-based protocols.

• Protocol Optimization: Serves as a critical bridge between T-flask research and large-scale manufacturing (e.g., Xuri W25), allowing for the validation of growth kinetics at a smaller, cost-effective scale.

• Single-Use Efficiency: Minimizes hands-on time and resource consumption by utilizing disposable plastics, allowing for faster turnaround between runs and increased lab productivity.

• Scalable Performance: Utilizes the same rocking geometry as larger Xuri systems, ensuring a seamless transition and predictable scale-up of cell expansion processes for clinical use.

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