Description
- Totally synthetic, cyclic peptide containing non-natural amino acids
- More stable than conventional growth factors
- Animal-component free
- Superior activity compared to recombinant Wnt3a in the TCF/LEF reporter assay, achieving the same level of activation at 1/70th mass concentration.
- 1 nM of PG-008 has the same level of efficiency as 3 µM of CHIR99021 in differentiation of iPSCs into definitive endoderm
- Work extracellularly unlike CHIR99021 and exhibit no cytotoxicity up to 10 uM, which is the highest concentration tested
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