Phenomenex Microplate 50 mg 96 Well Box with 2 Plates

Description

Phenomenex Strata C18-T Solid Phase Extraction (SPE) Microplate – 96-Well, 50 mg Sorbent Per Well, 55 Micron, 140 Angstrom, Polypropylene, Non-Sterile (MPN: 8E-S004-DGB)

The Phenomenex 8E-S004-DGB (also cataloged under the Strata product line) is a premium, high-throughput 96-well solid phase extraction (SPE) filter microplate engineered for target analyte clean-up, sample concentration, and desalting prior to LC-MS, LC-MS/MS, or HPLC downstream testing. Molded from high-purity, solvent-inert polypropylene, each individual well features a maximum volume capacity of 2 mL and comes pre-packed with 50 mg of Strata C18-T sorbent. This specialized, silica-based octadecyl phase features an expanded 140 Angstrom pore size and endcapped chemistry, making it uniquely optimized for extracting large hydrophobic molecules, peptides, and proteins up to 75 kDa from complex biological matrices, environmental samples, and food extracts.

Technical Performance and Design

• Strata C18-T Wide-Pore Sorbent Phase: Packed with silica-based C18-T particles featuring a 55 micron diameter and an expanded 140 Angstrom pore structure. This wide-pore configuration allows large hydrophobic biomolecules and proteins to fully access the bonded phase without steric hindrance or well plugging.

• Efficient Chemical Endcapping: The sorbent undergoes a rigorous endcapping process to clear away residual silanol groups. This action eliminates unwanted secondary polar interactions, ensuring clean reversed-phase separation mechanics and reliable target analyte recovery rates.

• Solvent-Resistant Polypropylene Housing: Fabricated from high-grade natural polypropylene that provides outstanding chemical resistance against aggressive processing solvents, including acetonitrile, methanol, and Dimethyl Sulfoxide (DMSO), without background extractable leaching.

• Uniform Drip Nozzle Flow Dynamics: The bottom of the 96-well matrix is outfitted with precision-molded drip nozzles that channel eluent cleanly down into collection plates. This layout prevents cross-well fluid bleed-over during vacuum manifold processing or automated centrifugation runs.

Product Specifications

• Catalog Number / MPN: 8E-S004-DGB (8ES004DGB)

• Manufacturer / Brand: Phenomenex / Strata SPE

• Format Layout: Standard 96-Well Grid (8 x 12 Array)

• Sorbent Mass Loading: 50 mg per individual well

• Sorbent Core Matrix: Silica-Based C18-T (Reversed Phase)

• Particle Physical Properties: 55 micron particle size / 140 Angstrom pore size (Surface area of 300 square meters per gram)

• Maximum Internal Well Capacity: 2 mL total volume

• Sterility / Process State: Non-Sterile (Solid Phase Extraction and Sample Prep Only)

• Standard Packaging: Box of 2 Plates total

Key Benefits and Applications

• Large Biomolecule Clean-up: The premier sample prep tool for trapping and isolating heavy hydrophobic organic molecules, peptides, small proteins, and veterinary drug residues from biological fluids like plasma or serum.

• Automated High-Throughput Workflows: Designed with standard ANSI/SLAS exterior sizing to fit seamlessly into automated liquid handling decks, automated SPE workstations, vacuum manifolds, and positive pressure systems.

• Mass Spectrometry Matrix Cleaning: Aggressively filters out salts, phospholipids, and particulate noise from crude extracts, extending the service lifespan of analytical columns and increasing MS ionization signals.

• Rigid Alphanumeric Identification Grid: The plate deck features high-contrast embossed grid borders (A to H, 1 to 12) for mistake-free sample positioning, mapping tracking, and easy identification loops under hoods.

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