Description
- High binding capacity for bispecific antibodies and antibody fragments containing the VH3 sequence family
- Provides good resolution for product-related impurities in the capture of bispecific antibodies
- Excellent alkaline stability; stable when cleaned with 05 M NaOH, minimizing risk for bioburden incidents and providing a long resin lifetime
- A single interaction with the Fab VH3 region is beneficial over a dual-interaction affinity ligand, as separation of unwanted mispaired antibodies and fragments from target bsAb may be more efficient
- Easily measure protein A leakage using the VH3 ligand ELISA kit specifically designed for use with MabSelect™ VH3 resin
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