Description
Description
Chloramphenicol ≥98% HPLC 500 Gram
Synonym:D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide, Chloromycetin
- CAS Number 56-75-7
- Linear Formula Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
- Molecular Weight 323.13
- Beilstein/REAXYS Number 2225532
- EC Number 200-287-4
- MDL number MFCD00078159
- PubChem Substance ID 24892250
- NACRES NA.76
| assay | ≥98% (HPLC) |
| form | powder or crystals |
| pKa | 5.5 |
| mp | 148-150 °C (lit.) |
| Mode of action | protein synthesis | interferes |
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| mycobacteria | |
| mycoplasma | |
| storage temp. | room temp |
| SMILES string | OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+]([O-])=O |
| InChI | 1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1 |
| InChI key | WIIZWVCIJKGZOK-RKDXNWHRSA-N |
| Gene Information | human … CYP1A2(1544) |
General description
Chemical structure: phenicole
Application
Chloramphenicol is a synthetic antibiotic, isolated from strains of Streptomyces venezuelae. It is often used for bacterial selection in molecular biology applications at 10-20μg/mL and as a selection agent for transformed cells containing chloramphenicol reistance genes.
Chloramphenicol has been used as a bacteriostatic non potent antibiotic. It has been used for the selection/growth of positive bacterial cells.
GHS08
Signal word Warning
Hazard statements H351
Precautionary statements P280
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AB6825000
Documents
Safety Data Sheet
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