Description
Corning 431405 Erlenmeyer Culture Flask – 125 mL, Baffled Bottom, Vent Cap, Sterile
The Corning 431405 is a high-performance 125 mL Erlenmeyer flask designed for the cultivation of suspension cell lines, bacteria, and yeast. Manufactured from medical-grade, high-clarity polycarbonate, this flask provides the transparency of glass with the safety and durability of shatterproof plastic. The flask features a molded-in baffled bottom, which promotes vigorous agitation and increases the surface-to-volume ratio to optimize gas exchange. Each flask is supplied individually wrapped and gamma-irradiated to ensure maximum sterility (SAL 10⁻⁶). Equipped with a 38 mm vented screw cap featuring a 0.2 µm hydrophobic membrane, the 431405 allows for continuous, sterile gas exchange while maintaining a secure barrier against contamination.
Technical Performance and Design
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Molded-in Baffled Bottom: The triple-baffle design creates a turbulent flow in the media during orbital shaking, significantly enhancing oxygenation for high-demand aerobic cultures.
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0.2 µm Vented Cap: The breathable cap ensures consistent gas exchange while preventing the entry of microorganisms, making it ideal for CO2 incubators.
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Individually Wrapped: Each flask is hermetically sealed in its own medical-grade packaging, preventing “cross-contamination” of unused stock and ensuring aseptic integrity until the moment of use.
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High-Clarity Polycarbonate: Constructed from USP Class VI resin, offering excellent visibility for monitoring cell density and media color while providing the impact resistance needed for high-speed shaking.
Product Specifications
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Catalog Number: 431405
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Capacity: 125 mL
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Material: Polycarbonate (PC)
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Bottom Style: Baffled
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Cap Size/Style: 38 mm Vented Cap
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Sterility: Sterile (Gamma Irradiated, SAL 10⁻⁶)
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Certifications: Non-pyrogenic, Non-cytotoxic, and RNase/DNase-free.
Key Benefits & Applications
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Aerobic Fermentation: The baffled geometry is the gold standard for E. coli and yeast cultures that require high oxygen levels to achieve maximum biomass.
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Mammalian Cell Culture: Frequently used for the expansion of CHO, HEK293, and other suspension lines where sterile gas exchange is critical.
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Disposable Efficiency: The single-use format eliminates the risks and costs associated with cleaning, autoclaving, and validation of glass flasks.
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Secure Tracking: Features molded-in graduations for accurate volume measurement and a large writing area for secure sample identification.
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