Description
Description
NN′-Methylenebisacrylamide Powder ≥99.5% 100 Gram
Synonym: BIS
- CAS Number 110-26-9
- Linear Formula (CH2=CHCONH)2CH2
- Molecular Weight 154.17
- Beilstein/REAXYS Number 1706297
- EC Number 203-750-9
- MDL number MFCD00008625
- PubChem Substance ID 24897151
- NACRES NB.22
| grade | for electrophoresis |
| for molecular biology | |
| assay | ≥99.5% |
| form | powder |
| impurities | ≤0.05% Free carboxylic acid (T) |
| ≤50 mg/kg Total sulfur (as SO4 ) (ICP) | |
| conductivity | ≤10 μmho (2% solution) |
| anion traces | chloride (Cl-): ≤50 mg/kg |
| cation traces | Ca: ≤10 ppm |
| Cd: ≤5 ppm | |
| Co: ≤5 ppm | |
| Cr: ≤5 ppm | |
| Cu: ≤5 ppm | |
| Fe: ≤5 ppm | |
| K: ≤50 ppm | |
| Mg: ≤5 ppm | |
| Mn: ≤5 ppm | |
| Na: ≤50 ppm | |
| Ni: ≤5 ppm | |
| Pb: ≤5 ppm | |
| Zn: ≤5 ppm | |
| absorption | ≤0.2 at 290 at 1% |
| foreign activity | DNase and RNase, none detected |
| SMILES string | C=CC(=O)NCNC(=O)C=C |
| InChI | 1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11) |
| InChI key | ZIUHHBKFKCYYJD-UHFFFAOYSA-N |
General description
N,N′-Methylenebisacrylamide is commonly called as bis. It is used as a cross-linking agent in the preparation of polyacrylamide gels consisting of chains of acrylamide monomers. The concentration of N,N′-methylenebisacrylamide and acrylamide determines the pore size of the gel. The higher concentration of bis forms rigid gels with smaller pores due to more cross-linking leading to polymerization and vice versa.
Application
N,N′-Methylenebisacrylamide has been used:
• as a crosslinker in the monomer solution to prepare N,N-dimethyl acrylamide (DMAAm)-based cryogel and acrylamide (AAm)-based cryogel matrix
• as a crosslinker to prepare tough hydrogel network
• in the preparation of acrylamide-bisacrylamide stock solution for the preparation of polyacrylamide gel
To be mixed with acrylamide for making polyacrylamide gels for use in protein and nucleic acid electrophoresis.
GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS AS3678000
Documents
Safety Data Sheet
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