Sonics Cup Horn 1.5 in. for Sonication

Description

Sonics & Materials 630-0607 Cup Horn – 1.5-inch (38 mm), Indirect Sonication

The Sonics 630-0607 is a precision-engineered 1.5-inch (38 mm) Cup Horn designed for the high-intensity indirect sonication of biological and chemical samples. Unlike traditional probes that must be immersed in the sample, the cup horn acts as a high-intensity ultrasonic water bath. By placing sealed tubes into the water-filled horn, researchers can process samples without the risk of cross-contamination, aerosolization, or probe erosion. Constructed from high-grade titanium alloy (Ti-6Al-4V), this cup horn is optimized for the 20 kHz Vibra-Cell™ ultrasonic processors, providing uniform cavitation for efficient cell disruption, DNA shearing, and nanoparticle dispersion while maintaining sample sterility.

Technical Performance and Design

• Indirect Sonication Advantage: Allows for the processing of samples inside sealed microcentrifuge tubes or vials. This prevents the formation of aerosols and eliminates the risk of sample-to-sample contamination or contamination from the titanium probe itself.

• High-Grade Titanium Alloy: Fabricated from Ti-6Al-4V, ensuring maximum acoustic transmission, exceptional fatigue strength, and resistance to corrosion, even during extended sonication cycles.

• Standard 20 kHz Compatibility: Specifically designed for use with Sonics & Materials 500-watt and 750-watt Vibra-Cell™ ultrasonic processors, ensuring perfect frequency matching for maximum cavitation energy.

• Effective Heat Dissipation: The water-filled chamber acts as a cooling medium. When used with a recirculating chiller, it allows for temperature-controlled sonication, which is vital for preventing the denaturing of proteins or heat-sensitive analytes.

Product Specifications

• Part Number: 630-0607

• Diameter: 1.5 inches (38 mm)

• Material: Titanium Alloy Ti-6Al-4V

• Compatibility: Sonics Vibra-Cell™ 20 kHz Systems (VC505, VCX500, VC750, VCX750)

• Application: Indirect/Sealed-Tube Sonication

• Connection: Standard 1/2-20 thread for attachment to the ultrasonic converter.

Key Benefits & Applications

• Genomics & DNA Shearing: Ideal for shearing DNA or chromatin into specific fragment sizes for NGS (Next-Generation Sequencing) while keeping the sample in a sterile, closed environment.

• Pathogen Research: Essential for processing infectious agents or biohazardous materials where containing aerosols is a primary safety requirement.

• High-Throughput Processing: When used with a tube holder, multiple samples can be sonicated simultaneously with identical energy intensity, ensuring high reproducibility across the batch.

• Nanoparticle Dispersion: Provides the intense energy needed to break up nanoparticle agglomerates in small volumes without introducing probe-tip impurities into the mixture.

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